You may think poor circulation and pain in your legs are to be expected as you get older. They're not. They may be symptoms of Peripheral Artery Disease, or P.A.D., a serious medical condition that more than doubles your risk of heart attack or stroke. P.A.D., or poor circulation in the legs as it is sometimes called, also puts you at more than 4 times the risk of dying from heart disease such as heart attack or stroke.

If you have pain or heaviness in the legs when you walk that goes away when you rest, there are ways to relieve the discomfort. Your doctor may recommend a variety of important treatments for your poor leg circulation. But these may not lower your risk of a heart attack or stroke. When discussing treatment, be sure to ask about reducing the risk of heart attack or stroke associated with P.A.D. with prescription Plavix® (clopidogrel bisulfate).

Leg pain associated with P.A.D. may indicate that the arteries in your legs are more than 60% blocked. Poor circulation in the legs may mean poor circulation in your heart and brain that more than doubles your risk of heart attack or stroke. That's why it's important to talk to your doctor about getting tested for poor circulation in the legs. If you're diagnosed, ask about treatment options, like PLAVIX, to help reduce your risk of heart attack or stroke.

PLAVIX is the only antiplatelet therapy FDA-approved to help reduce the risk of future heart attack or stroke in patients with established P.A.D.

Remember to talk to your doctor about any concerns regarding your health or before beginning any sort of exercise or change in your diet.

Learn more about P.A.D.

PLAVIX is prescribed to lower the risk of future heart attack or stroke in patients with established Peripheral Artery Disease.

Important Safety Information: Certain genetic factors and some medicines such as Prilosec reduce the effect of PLAVIX leaving you at greater risk for heart attack and stroke. Your doctor may use genetic tests to determine treatment. Don’t stop taking PLAVIX without talking to your doctor as your risk of heart attack or stroke may increase. People with stomach ulcers or conditions that cause bleeding should not use PLAVIX. Taking PLAVIX alone or with some other medicines, including aspirin, may increase bleeding risk, so tell your doctor when planning surgery. Tell your doctor all medicines you take, including aspirin, especially if you’ve had a stroke. If fever, unexplained weakness or confusion develops, tell your doctor promptly. These may be signs of TTP, a rare but potentially life-threatening condition, reported sometimes less than 2 weeks after starting PLAVIX. Other rare but serious side effects may occur.

Please see Full Prescribing Information Including Boxed Warning for more details.

The health information contained herein is provided for general educational
purposes only. Your health-care professional is the single best source of
information regarding your health. Please consult your health-care professional if
you have any questions about your health or treatment.