Many people with Peripheral Artery Disease (P.A.D.), often described as poor circulation in the legs, won't notice any symptoms. If you are over 50 with risks for heart disease, such as high blood pressure, high cholesterol, diabetes, or smoking, you are at a greater risk of having P.A.D. And it's important to know that P.A.D. more than doubles your risk of heart attack or stroke. A 2007 survey of adults at least 50 years old, conducted by the P.A.D. Coalition, showed that even people who were aware of P.A.D. did not know the risk factors for it. Click here for more information on risk factors.

You may be taking other medicines to lower your cholesterol or blood pressure. These medicines are important and can help reduce your overall cardiovascular risk. However, you may still need to talk to your doctor about getting tested for P.A.D. And, if you are diagnosed with P.A.D., you are at more than double the risk for heart attack or stroke. There may be more you can do to help prevent blood clots from increasing your risk of stroke or heart attack.

Plavix® (clopidogrel bisulfate) can help lower that risk. PLAVIX is the only antiplatelet therapy FDA-approved to help reduce the risk of future heart attack or stroke in patients with established P.A.D.

Blood clots cause over 90% of heart attacks and 85% of strokes. PLAVIX is proven to help keep platelets in the blood from sticking together and forming blood clots, which helps keep blood flowing. This can help protect you from a future heart attack or stroke. That's why it's important to talk to your doctor about treatment options, like PLAVIX, to reduce your risk of a heart attack or stroke.

Learn more about P.A.D.

PLAVIX is prescribed to lower the risk of future heart attack or stroke in patients with established Peripheral Artery Disease.

Important Safety Information: If you have a stomach ulcer or other condition that causes bleeding you should not use PLAVIX. Taking PLAVIX alone or with some other medicines including aspirin may increase bleeding risk. Tell your doctor before planning surgery or taking aspirin or other medicines with PLAVIX, especially if you've had a stroke. Some medicines that are used to treat heartburn or stomach ulcers, like Prilosec, may affect how PLAVIX works, so tell your doctor if you are taking other medicines. If fever, unexplained weakness or confusion develops, tell your doctor promptly. These may be signs of TTP, a rare but potentially life-threatening condition, reported sometimes less than 2 weeks after starting PLAVIX. Other rare but serious side effects may occur.

Please see full prescribing information for more details.

The health information contained herein is provided for general educational
purposes only. Your health-care professional is the single best source of
information regarding your health. Please consult your health-care professional if
you have any questions about your health or treatment.